توسعه کامپوزیتهای پلیمری ساخته شده ازپلیمرهای قالبمولکولی با تلفیق آنها با چارچوبهای آلی–کووالانسی و فلز-آلی برای کاربردهای زیستمحیطی، علوم پزشکی و ایمنی غذایی
محورهای موضوعی :زهرا سلیمی بروجنی 1 , بنت الهدی حسینیان 2 , میلاد غنی 3 *
1 - دانشگاه مازندران
2 - دانشگاه مازندران
3 - دانشگاه مازندران
کلید واژه: پلیمرهای با قالبمولکولی, چارچوبهای فلز–آلی, چارچوبهای آلی–کووالانسی, کامپوزیتها و آمادهسازی نمونه,
چکیده مقاله :
بهکارگیری جاذبهایی با ساختارهای جدید و مهندسیشده، با قابلیت برقراری ارتباط اختصاصی با گونه هدف و دامنه کاربرد گسترده، رویکردی نوآورانه و کارآمد در روشهای تجزیهای خصوصا با کاربردهای زیست محیطی، بهشمار میآید. فناوریهای آمادهسازی نمونه مبتنی بر پلیمرهای با قالبمولکولی، این پتانسیل را دارند که بخش عمدهای از الزامات یک سیستم ایدهآل آمادهسازی نمونه را برآورده کنند. با این حال، به دلیل برخی محدودیتها و کاستیهای ذاتی، همچنان تردیدهایی در مورد بهرهوری و قابلیت کاربرد عملیMIPهای متداول وجود دارد. ادغام MIPها با مواد عملکردی پیشرفته، نهتنها راهکار مؤثری برای رفع این چالشها فراهم میکند، بلکه دامنه کاربرد این کامپوزیتها را بهطور چشمگیری گسترش میدهد. این مقاله، مروری به بررسی تازهترین پیشرفتها در راهبردهای سنتز و کاربردهای کامپوزیتهای مبتنی بر چارچوبهای فلز–آلی (MOFs) و چارچوبهای آلی–کووالانسی (COFs) در تکنیکهای مختلف آمادهسازی نمونه میپردازد. برای این منظور، ایتدا مقدمه ای در خصوص چارچوب های فلز-آلی و آلی-کوالانسی مطرح خواهد شد. افزون بر این، ویژگیهای خاصMIPها مرور شده و خصوصیات ساختاری و عملکردیMOFها وCOFها بهعنوان جاذبهای پیشرفته مورد بحث قرار میگیرد. در ادامه، جدیدترین دستاوردها در طراحی و ساخت کامپوزیتهای MIP مبتنی بر MOF و COF با تأکید بر کاربردهای عملی آنها جمعبندی شده و در پایان، چالشها و چشماندازهای آینده برای توسعه روشهای تجزیهای مبتنی بر این مواد تشریح میگردد.
The use of engineered sorbents with selective recognition capabilities, selective interactions with the target analytes and broad applicability represents an innovative and efficient approach in analytical methodologies, particularly for environmental applications. Sample preparation technologies based on molecularly imprinted polymers (MIPs) have the potential to meet many of the key requirements of an ideal sample preparation system. Nevertheless, due to several inherent limitations, uncertainties still remain regarding the efficiency and practical applicability of conventional molecularly imprinted polymers. Integrating molecularly imprinted polymers with advanced functional materials not only provides an effective solution to these challenges but also significantly expands the application range of these composites. This review discusses recent advancements in the synthesis strategies and analytical applications of composites based on metal–organic frameworks (MOFs) and covalent organic frameworks (COFs) in various sample preparation techniques. Additionally, the inherent features of MIPs are summarized, and the structural and functional properties of MOFs and COFs as advanced sorbents are examined. Furthermore, the most recent developments in the design and fabrication of MOF- and COF-based MIP composites, with an emphasis on their practical applications, are presented. Finally, the existing challenges and future perspectives for the development of analytical methodologies based on these materials are outlined.
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